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KMID : 0960920030020010065
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Dementia and Neurocognitive Disorders
2003 Volume.2 No. 1 p.65 ~ p.69
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A Case of Sporadic Creutzfeldt-Jakob Disease with Motor Neuron Disease
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Yoo Bong-Goo
Kim Kwang-Soo
Yoo Kyung-Moo
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Abstract
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Dementia with motor neuron disease includes frontotemporal dementia with motor neuron disease, amyotrophic Creutzfeldt-Jakob disease, Parkinson-amyotrophic lateral sclerosisdementia complex, familial amyotrophic lateral sclerosis, and hereditary spastic paraparesis. A 54-year-old man presented with a eight month history of rapidly progressive dementia. Progressively more severe dementia was accompanied by muscle wasting and visible fasciculations. Cerebrospinal fluid showed the 14-3-3 protein. Brain MRI revealed mild diffuse atrophy in both frontal, temporal and parietal lobes. He died 9 months after onset of the disease. We report a patient with sporadic Creutzfeldt-Jakob disease with motor neuron disease.
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KEYWORD
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Creutzfeldt-Jakob disease, Motor neuron disease, Dementia
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